16. Ghent, Belgium Ghent is a port city in northwest Belgium, at the confluence of the Leie and Scheldt rivers. During the Middle Ages it was a prominent city-state. Today it’s a university town and cultural hub. Its pedestrianized center is known for medieval architecture such as 12th-century Gravensteen castle and the Graslei, a row of guildhalls beside the Leie river harbor.