Spurts of high energy, hours or even days without sleep leave you lethargic with aching muscles and sick to your stomach when you are without the drugs. Too much or too little sleep affects every system in your body and therefore your body learns to function the best way it can, which usually translates to functioning only when on the drugs. Your body will crave the drug in order not to hurt, not be violently ill, to sleep or to stay awake.