Movies that permanently damaged actors' bodies

Nicole Kidman in Moulin Rouge (2001)
 The anachronistic musical spectacular Moulin Rouge was pretty hard on star Nicole Kidman, who fell down the stairs during a dance number and injured her right knee. Due to delays and recovery, the incident led to a $3 million insurance loss. The knee continued to give her problems, which caused Kidman to drop out of Panic Room, which she'd already started filming for three weeks. Briefly uninsurable, she had to hold part of her salary in escrow just to be able to film her part in Cold Mountain. That's a lot of trouble for playing a singing courtesan.