One of the most serious consequences of a sedentary lifestyle is the risk of cardiovascular diseases like coronary heart disease or chronic hypertension. A life of continuous sitting weakens the muscles, deteriorates blood circulation and lowers the tone of blood vessels. A lack of physical activity is one of the main reasons for early atherosclerosis (a build-up of cholesterol plaques in the blood vessels of the heart). Also, an imbalance between the oxygen supply and consumption can occur, where the heart needs more oxygen than the blood is bringing.
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