So, what can you do? Well, pollution is thought to make it worse, so a hat or a headscarf might do the trick, but sunlight is also thought to combat it, so take it off when the sun comes out. Most anti-dandruff shampoos will simply wash the dandruff out of your hair by exfoliating the scalp, but it won't tackle the root of the problem. If your dandruff is making you particularly miserable, then the best thing to do is to use an antifungal shampoo and exterminate the blighters.Shampoos containing ketoconazole should do the trick, although M. globosa can develop a resistance, so use it sparingly. In the long term, those lovely people over at Head and Shoulders have actually managed to sequence the DNA of the fungus in the hope that it will lead to a once-and-for-all treatment for dandruff.