If your gut microbiome is off-balance, you'll end up with gas, bloating, and a not-so-flat stomach, Dr. Nusbaum says. Pamela Merino, MD, an internist in Miami, Florida, says, however, that more research is necessary into how gut health affects fat storage specifically. Dr. Merino points to research showing that stool transplants from thin people to overweight people result in weight loss—and the only explanation is that thin people's microbiomes are better at burning fat.