After his return, he was employed in Iranian National Oil Company. He went on to become VP to Prime Minister Hassan Ali Mansur. He was later the director of Kaakh Javanan. He became the mayor of Tehran in 1346 AH. After his tenure as mayor, he went to become the representative of Isfahan in Iranian senate. He was later arrested during political arrests later that year. During the Iranian revolution Nikpey was in jail in Tehran and was freed by the revolutionaries.