What causes gray hair? For most people, it’s age-related. As your hair follicles (and you) age, they produce less color, so when you go through the natural cycle of shedding and growing new hairs, they’re more likely to come in gray after a certain age (typically around 35). That said, genetics factor heavily into this, which is why some people start to gray in their twenties, while others won’t notice a significant change in color until their 40s.