How chronic diseases can affect personality?

Bipolar Disorder

This causes mood changes that go way beyond the normal ups and downs of daily life. When you're up, you might feel jumpy, talk really fast, and take big risks. When you're down, you might be worried, have low energy, and feel worthless. And sometimes, you might feel a mix of both. These intense changes can mess with your sleep and energy, and make it hard to think clearly.