She started appearing on television specials in the mid 2000s and over a period of time quit her legal career to focus more on her television appearances. In 2011, Guilfoyle was chosen as a co-host for the ‘The Five,’ a news and talk show on Fox News Channel featuring a rotating panel who discuss current stories, political issues, and pop culture, a post that earned her much name and fame as a news personality. In mid-2017 it was reported that Guilfoyle was being considered to serve as press secretary for President Donald Trump. However, the reports were later dismissed.