Make sure that you are able to create a niche by having a separate vision from other galleries in town or in your area. Keep your vision consistent. Don't back down or change your vision just because sales are low initially. Become an expert in your niche. Choose a type of work that you have a depth of knowledge in. Work to become extremely knowledgable in each piece you place in your gallery, even if you don't know everything about the art world in general. Buyers will feel more comfortable if you are able to explain each piece in depth and place it in context within the genre.