HCM is a genetic heart condition that affects up to 1 in 167 peopleTrusted Source. In HCM, the muscles of the left ventricle become thickened and enlarged, which can result in a reduced left ventricle volume and impaired activity of the aortic valve. These effects can make it more difficult for the heart to pump blood to the rest of the body, place strain on the heart and lungs, and disrupt typical heart rhythms. In most cases, HCM is benign, and many people may not even experience symptoms. In some cases, though, heart complications can develop. Sudden cardiac death may occur in up to 0.6%Trusted Source of people with HCM per year.