Ayatollah Khomeini, the leader of the Islamic Revolution in Iran in 1979 and the founder of the Islamic Republic of Iran, had a significant impact on the Middle East region in a number of ways: 1. Ideological Influence: Khomeini's brand of Shia Islamic fundamentalism and his calls for revolution against oppressive regimes inspired other Islamist movements and groups in the region. His teachings and writings have influenced various Islamist organizations and movements, including Hezbollah in Lebanon.