High levels of stress and pressure from demanding careers can have a detrimental impact on personal relationships. When individuals are constantly feeling overwhelmed and anxious about their work, they may have less energy and time to devote to their significant others, family, and friends. This can lead to feelings of neglect, resentment, and frustration within the relationship. Additionally, the emotional strain of dealing with work-related stress may cause individuals to become irritable, moody, and easily agitated, making it difficult to communicate effectively and resolve conflicts in a healthy manner.