He quickly established himself as a leading expert in the field, publishing numerous papers on brain tumors, head injuries, and other neurological conditions. In 1905, Cushing performed the first successful removal of a pituitary tumor, a procedure that would become a hallmark of his work. Cushing's success at Johns Hopkins led to his appointment as the chief of surgery at the newly established Peter Bent Brigham Hospital in Boston in 1912. It was here that Cushing solidified his reputation as a world-class neurosurgeon, pioneering new techniques in surgery and developing innovative treatments for a wide range of neurological conditions. One of Cushing's most significant contributions to the field of neurosurgery was his development of the "Cushing reflex," a physiological response to increased intracranial pressure.
