10 Warning Signs That Your Immune System Is Malfunctioning

7. Migratory and Morning Joint Pain
Painful, swollen, and stiff joints—especially in the morning lasting more than 30 minutes—are classic signs of Rheumatoid Arthritis (RA). In this autoimmune disease, the defense system attacks the synovium (the lining of the joints), causing inflammation and cartilage destruction. If ignored, chronic inflammation can lead to bone deformity and permanent disability. These pains indicate that the immune system is eroding the joints instead of lubricating them.