4. Cardiovascular Risks and Increased Stroke Probability
Extensive research indicates that long-term or high-dose use of certain NSAIDs can increase the risk of serious cardiovascular events, including heart attacks and strokes. These drugs can disturb the balance of chemicals responsible for blood vessel contraction and clotting. Furthermore, due to sodium and water retention, many users experience increased blood pressure, which is a significant risk factor for heart failure—a critical issue for those with pre-existing heart conditions.
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