Hypothetical mechanisms involved in chronic stress sensitizes to pancreatitis. Chronic stress compromises the exocrine pancreas by generating ischaemia and reperfusion processes, as well as attracting leukocytes to the pancreatic parenchyma.Pancreatitis, a debilitating and sometimes deadly inflammation of the pancreas, can be acute or chronic. It accounts for about 275,000 U.S. hospitalizations each year, with its incidence on the rise for reasons that are unclear. The many causes of pancreatitis include long-term alcohol abuse, gallstones, and certain inherited conditions, according to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health (NIH).
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