The combination of potassium with the fruit's anti-inflammatory and antioxidant compounds—especially the flavonoids—helps to relax blood vessels, enhance circulation, and prevent the hardening of the arteries. This comprehensive action on the vascular system underscores persimmon's role in the primary prevention of hypertension, stroke, and overall heart disease.Beyond their cardiovascular and digestive benefits, persimmons are recognized for their supportive role in metabolic health and potentially in blood sugar regulation. While they do contain natural sugars, the high fiber content helps to slow down the absorption of glucose into the bloodstream, resulting in a more gradual and sustained energy release rather than a sharp spike. Certain bioactive compounds, particularly the tannins found in the fruit, have been investigated for their potential to inhibit $\alpha$-amylase and $\alpha$-glucosidase enzymes, which are responsible for carbohydrate digestion.
